产品名称

英文名称：2-Methyl-6-nitrobenzoic anhydride

同义词

2-Methyl-6-nitrobenzoic anhydride、434935-69-0、MNBA、6-Nitro-o-toluic Anhydride、Benzoic acid, 2-methyl-6-nitro-, anhydride、(2-methyl-6-nitrobenzoyl) 2-methyl-6-nitrobenzoate、EC8MK6FE8B、2-methyl-6-nitrobenzoic acid anhydride、MFCD06797117、2-METHYL-6-NITROBENZ、6-硝基邻甲苯酸酐

产品性质

CAS编号：434935-69-0

分子式：C16H12N2O7

分子量：344.28

MDL号：MFCD06797117

PubChem编号：10472648

别名：6-硝基邻甲苯酸酐

英文别名：2-Methyl-6-nitrobenzoic anhydride|434935-69-0|MNBA|6-Nitro-o-toluic Anhydride|Benzoic acid, 2-methyl-6-nitro-, anhydride|(2-methyl-6-nitrobenzoyl) 2-methyl-6-nitrobenzoate|EC8MK6FE8B|2-methyl-6-nitrobenzoic acid anhydride|MFCD06797117|2-METHYL-6-NITROBENZ

规格或纯度：>98.0%(HPLC)

英文名称：2-Methyl-6-nitrobenzoic anhydride

储存温度：充氩

运输条件：常规运输

产品介绍：用于制备多种大环内酯类天然产物的多功能内酯化试剂。介绍2-甲基-6-硝基苯甲酸酐可用作酰胺、内酯、酯和肽合成中的偶联促进剂用途2-甲基-6-硝基苯甲酸酐可用于作为多功能的内酯化试剂用于制备各种大环内酯天然产物和内酯。作为反应促进剂采用相应的胺和羧酸合成羧酰胺衍生物。GRP78 抑制剂 prunustatin A、抗真菌化合物 (3R,16E,20E,23R)-(−)-eushearilide 和防肥胖药四氢利泼斯汀的全合成。A versatile lactonization reagent used in the preparation of a variety of macrolide natural products.product description2-Methyl-6-nitrobenzoic anhydride is a reagent employed as a coupling promoter in the synthesis of amides, lactones, esters, and peptides.application2-Methyl-6-nitrobenzoic anhydride can be usedAs a versatile lactonization reagent applicable in the preparation of varieties of macrolide natural products and lactones.As a reaction promoter in the synthesis of carboxamide derivatives by using corresponding amines and carboxylic acids.In the total synthesis of GRP78 inhibitor prunustatin A, antifungal compound (3R,16E,20E,23R)-(−)-eushearilide and an antiobestic drug tetrahydrolipstatin.

IUPAC Name：(2-methyl-6-nitrobenzoyl) 2-methyl-6-nitrobenzoate

INCHI：InChI=1S/C16H12N2O7/c1-9-5-3-7-11(17(21)22)13(9)15(19)25-16(20)14-10(2)6-4-8-12(14)18(23)24/h3-8H,1-2H3

InChi Key：YEKPNMQQSPHKBP-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C(=CC=C1)[N+](=O)[O-])C(=O)OC(=O)C2=C(C=CC=C2[N+](=O)[O-])C

Isomeric SMILES：CC1=C(C(=CC=C1)[N+](=O)[O-])C(=O)OC(=O)C2=C(C=CC=C2[N+](=O)[O-])C

WGK Germany：3

PubChem CID：10472648

Reaxy-Rn：3480189

敏感性：对湿度敏感

熔点：177 °C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：dust mask type N95 (US)， Eyeshields， Gloves

产品包装