产品名称

英文名称：Orotic acid

同义词

Orotic acid、65-86-1、6-Carboxyuracil、Oropur、Orodin、Orotonin、Orotyl、Orotonsan、Vitamin B13、Whey factor、Oroturic、2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid、Uracil-6-carboxylic acid、Animal galactose factor、6-Uracilcarboxylic acid、Molkensaeure、Oro、1,2,3,6-四氢-2,6-二氧代-4-嘧啶羧酸、尿嘧啶-6-羧酸、2,6-二羟基嘧啶-4-羧酸、6-羧基-2,4-二羟基嘧啶、脲嘧啶-6-羧酸

产品性质

CAS编号：65-86-1

分子式：C5H4N2O4

分子量：156.1

Beilstein号：383901

EC号：200-619-8

MDL号：MFCD00006027

PubChem编号：967

别名：1,2,3,6-四氢-2,6-二氧代-4-嘧啶羧酸|尿嘧啶-6-羧酸|2,6-二羟基嘧啶-4-羧酸|6-羧基-2,4-二羟基嘧啶|脲嘧啶-6-羧酸

英文别名：Orotic acid|65-86-1|6-Carboxyuracil|Oropur|Orodin|Orotonin|Orotyl|Orotonsan|Vitamin B13|Whey factor|Oroturic|2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid|Uracil-6-carboxylic acid|Animal galactose factor|6-Uracilcarboxylic acid|Molkensaeure|Oro

规格或纯度：>98.0%

英文名称：Orotic acid

生化机理：在嘧啶代谢中起作用。增加体内肝三酰甘油水平。心脏保护。

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Orotic acid is a heterocyclic compound and an acid. It was once believed to be part of the vitamin B complex and was called vitamin B13, but it is now known that it is not a vitamin but is instead manufactured in the body by intestinal flora. Its salts, known as orotates, are sometimes used as mineral carriers in some dietary supplements, to increase their bioavailability. It is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid, forming pyrophosphate and orotidine 5′-monophosphate (OMP). It may be used to study dependent cell signaling pathways and transcription regulation mechanisms that induce hepatic lipogenesis.An intermediate in de novo pyrimidine biosynthesis.Orotic acid is a heterocyclic compound and an acid. It was once believed to be part of the vitamin B complex and was called vitamin B13, but it is now known that it is not a vitamin but is instead manufactured in the body by intestinal flora. Its salts, known as orotates, are sometimes used as mineral carriers in some dietary supplements, to increase their bioavailability. It is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid, forming pyrophosphate and orotidine 5′-monophosphate (OMP). It may be used to study dependent cell signaling pathways and transcription regulation mechanisms that induce hepatic lipogenesis.An intermediate in de novo pyrimidine biosynthesis.

PubChem SID：488179577

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488179577

IUPAC Name：2,4-dioxo-1H-pyrimidine-6-carboxylic acid

INCHI：InChI=1S/C5H4N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)

InChi Key：PXQPEWDEAKTCGB-UHFFFAOYSA-N

Canonical SMILES：C1=C(NC(=O)NC1=O)C(=O)O

Isomeric SMILES：C1=C(NC(=O)NC1=O)C(=O)O

WGK Germany：3

RTECS：RM3180000

PubChem CID：967

Wikipedia：Orotic_acid

ChEBI：CHEBI16742

CAS Registry No.：65-86-1

ChEMBL Ligand：CHEMBL1235017

RCSB PDB Ligand：ORO

DrugCentral Ligand：3402

溶解性：Soluble in Sodium Hydroxide

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

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