产品名称

英文名称：Tanshinone IIA

同义词

CHEBI108595、KBio2_000317、NCGC00095709-04、Phenanthro[1,11-dione, 6,7,8,9-tetrahydro-1,6,6-trimethyl-、MLS006011834、TANSHINONE IIA (CONSTITUENT OF CHINESE SALVIA)、BCP28199、1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione、SR-01000758926、丹参酮 IIA

产品性质

CAS编号：568-72-9

分子式：C19H18O3

分子量：294.34

MDL号：MFCD00238692

PubChem编号：164676

别名：丹参酮 IIA

英文别名：CHEBI108595|KBio2_000317|NCGC00095709-04|Phenanthro[1,11-dione, 6,7,8,9-tetrahydro-1,6,6-trimethyl-|MLS006011834|TANSHINONE IIA (CONSTITUENT OF CHINESE SALVIA)|BCP28199|1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione|SR-01000758926

规格或纯度：98%

英文名称：Tanshinone IIA

生化机理：从丹参中分离出的主要丹参酮。抑制NF-κB和AP-1 DNA结合。在许多不同的癌细胞中表现出细胞毒活性。抑制β-淀粉样蛋白聚集并保护PC12细胞免受β-淀粉样蛋白诱导的细胞凋亡的影响。显示抗氧化和抗炎特性。

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：浅红棕色、樱红色针状晶体。在甲醇、乙醇、氯仿、丙酮中溶解，在水中不溶。 Tanshinone IIA (Dan Shen ketone), vasoactive cardioprotective drμg, is used in a wide variety of studies to asses is potential therapeutic value and mechanisms of action which include inhibiting LDL oxidation, monocyte adhesion to endothelium, smooth muscle cell migration and proliferation, macrophage cholesterol accumulation, proinflammatory cytokine expression and platelet aggregation.Tanshinone IIA (Dan Shen ketone), vasoactive cardioprotective drug, is used in a wide variety of studies to asses is potential therapeutic value and mechanisms of action which include inhibiting LDL oxidation, monocyte adhesion to endothelium, smooth muscle cell migration and proliferation, macrophage cholesterol accumulation, proinflammatory cytokine expression and platelet aggregation.

IUPAC Name：1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione

INCHI：InChI=1S/C19H18O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,9H,4-5,8H2,1-3H3

InChi Key：HYXITZLLTYIPOF-UHFFFAOYSA-N

Canonical SMILES：CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C

Isomeric SMILES：CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C

WGK Germany：3

RTECS：SF8282695

PubChem CID：164676

Reaxy-Rn：288781

溶解性：溶于DMSO, 最高浓度 (mg/mL) 1.47, 最高浓度(mM) 5 温和加热

密度：1.209

敏感性：对热敏感

熔点：209°C-210°C

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装