产品名称

英文名称：Estrone

同义词

2DI9HA706A、Cristallovar、delta-1,3,5-estratrien-3-beta-ol-17-one、delta-1,3,5-Estratrien-3beta-ol-17-one、ESTRONE [USP-RS]、NSC-9699、Ovifollin、Unden (pharmaceutical)、Estrona [INN-Spanish]、Thelykinin、Wynestron、Estrone [USPINNBAN]、Ketodestrin、Oestroform、UNII-、雌甾酮

产品性质

CAS编号：53-16-7

分子式：C18H22O2

分子量：270.37

Beilstein号：1915077

EC号：200-164-5

MDL号：MFCD00003620

PubChem编号：5870

别名：雌甾酮

英文别名：2DI9HA706A|Cristallovar|delta-1,3,5-estratrien-3-beta-ol-17-one|delta-1,3,5-Estratrien-3beta-ol-17-one|ESTRONE [USP-RS]|NSC-9699|Ovifollin|Unden (pharmaceutical)|Estrona [INN-Spanish]|Thelykinin|Wynestron|Estrone [USPINNBAN]|Ketodestrin|Oestroform|UNII-

规格或纯度：>98.0%

英文名称：Estrone

生化机理：雌酮是一种黄体产生的溶黄体雌激素.雌激素。在体内显示出致癌和神经保护作用。

应用：该品是1号避孕药用的激素类药炔雌醇的中间体。

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：溶于醇、丙酮、二氧六环、苯、氯仿、吡啶及氢氧化碱溶液，微溶于醚和植物油，几乎不溶于水,水中溶解度0.03 g/L。 Estrone is an estrogenic hormone. Target Estrogen Receptor/ERR Estrone (E1) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy. Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.该品是1号避孕药用的激素类药炔雌醇的中间体。Estrone is an estrogenic hormone. Target Estrogen Receptor/ERR Estrone (E1) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy. Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.

IUPAC Name：(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one

INCHI：InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1

InChi Key：DNXHEGUUPJUMQT-CBZIJGRNSA-N

Canonical SMILES：CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O

Isomeric SMILES：C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)O

WGK Germany：3

RTECS：KG8575000

PubChem CID：5870

溶解性：DMSO 33.33 mg/mL (123.28 mM; Need ultrasonic) H2O < 0.1 mg/mL (insoluble)

密度：1.164

比旋光度：165 ° (C=1, Dioxane)

熔点：258-260°C

象形图：

信号词：Danger

危险声明：H351 Suspected of causing cancerH412 Harmful to aquatic life with long lasting effectsH302 Harmful if swallowedH312 Harmful in contact with skinH332 Harmful if inhaledH360 May damage fertility or the unborn childH350 May cause cancerH361 Suspected of damaging fertility or the unborn childH362 May cause harm to breast-fed children

预防措施声明：P261,P273,P280,P302+P352,P321,P405,P501,P264,P260,P271,P270,P304+P340,P362+P364,P330,P263,P203,P301+P317,P318,P317

Merck Index：3708

个人防护装备：Eyeshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges

产品包装