产品名称

英文名称：Daminozide

同义词

Daminozide、1596-84-5、Aminozide、Succinic acid 2,2-dimethylhydrazide、ALAR、DMASA、Kylar、N-(Dimethylamino)succinamic acid、Dimas、SADH、B-Nine、DYaK、Butanedioic acid, mono(2,2-dimethylhydrazide)、Alar 85、Dimethylaminosuccinamic acid、4-(2,2-dimethylhydrazinyl)-4-oxo、B9、比久、N-二甲胺基琥珀酰胺、单(2,2-二甲基酰肼)丁二酸酰肼、琥珀酸-2,2-二甲基酰肼

产品性质

CAS编号：1596-84-5

分子式：C6H12N2O3

分子量：160.17

Beilstein号：1863230

EC号：216-485-9

MDL号：MFCD00002787

PubChem编号：15331

别名：B9|比久|N-二甲胺基琥珀酰胺|单(2,2-二甲基酰肼)丁二酸酰肼|琥珀酸-2,2-二甲基酰肼

英文别名：Daminozide|1596-84-5|Aminozide|Succinic acid 2,2-dimethylhydrazide|ALAR|DMASA|Kylar|N-(Dimethylamino)succinamic acid|Dimas|SADH|B-Nine|DYaK|Butanedioic acid, mono(2,2-dimethylhydrazide)|Alar 85|Dimethylaminosuccinamic acid|4-(2,2-dimethylhydrazinyl)-4-oxo

规格或纯度：99%

英文名称：Daminozide

生化机理：Description IC50 Value N/A Inhibition of shoot elongation in dwarf and tall peas by the 1,1-dimethylhydrazide of succinic acid (B-995) was correlated with the inhibition of the oxidation of tryptamine-2-C(14) to indoleacetaldehyde-2-C(14) in homogenates prepared from epicotyls of young plants treated with B-995. The growth-retarding action of B-995 is attributed to the formation of 1,1-dimethylhydrazine in vivo. This hydrazine strongly inhibited tryptamine oxidation by pea epicotyl homogenates[1]. Daminozide (N-(dimethylamino)succinamic acid, 160 Da), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily[2]. in vitro Essential oil content increased with increasing levels of gibberellins and decreased when gibberellin biosynthesis was blocked withdaminozide. With increasing levels of gibberellins, 1,8-cineole and camphor contents increased. Daminozide blocked the accumulation of alpha- and beta-thujone.[3]. in vivo N/A Clinical trial N/A.Selective histone demethylase KDM2/7 subfamily inhibitor (IC 50 values are 0.55, 1.5 and 2.1 μM for PHF8, KDM2A and KDM7A respectively). Exhibits ≥ 60-fold selectivity for KDM2/7 demethylases over other histone demethylases (KDM3, KDM4, KDM5, KDM6) and 2-

应用：比久是一种生长抑制剂。它可抑制内源赤霉素的生物合成，也可抑制内源生长素的合成.

储存温度：充氩

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：不溶于一般的碳氢化合物。贮存稳定性好。Product IntroductionDaminozide is a commonly used plant growth regulator, which acts by inhibiting 2-oxoglutarate-dependent dioxygenase activity in the gibberellin biosynthesis pathway.ApplicationDaminozide may be used as a reference standard for the determination of daminozide in fruits and vegetables by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). It may also be used as a reference standard for the determination of daminozide in Ophiopogon japonicus plants and soil by ultra-performance liquid chromatography-triple quadrupole tandem mass spectrometry (UPLC-QqQ-MS/MS). Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

PubChem SID：488182105

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488182105

IUPAC Name：4-(2,2-dimethylhydrazinyl)-4-oxobutanoic acid

INCHI：InChI=1S/C6H12N2O3/c1-8(2)7-5(9)3-4-6(10)11/h3-4H2,1-2H3,(H,7,9)(H,10,11)

InChi Key：NOQGZXFMHARMLW-UHFFFAOYSA-N

Canonical SMILES：CN(C)NC(=O)CCC(=O)O

Isomeric SMILES：CN(C)NC(=O)CCC(=O)O

WGK Germany：2

RTECS：WM9625000

PubChem CID：15331

Reaxy-Rn：1863230

CAS Registry No.：1596-84-5

ChEMBL Ligand：CHEMBL2164243

Wikipedia：Daminozide

RCSB PDB Ligand：DZA

溶解性：溶于水，不溶于烃类。

密度：1.183

敏感性：对空气敏感

熔点：154-155°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritation

预防措施声明：P305+P351+P338,P280,P302+P352,P321,P264,P362+P364,P264+P265,P337+P317,P332+P317

Merck Index：2810

个人防护装备：Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

产品包装