产品名称

英文名称：1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine hydrate

同义词

ET-18-OCH3、77286-66-9、(R)-edelfosine、Edelfosine, (R)-、1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholine、LZ198HY9OE、TLC-ELL-12、CHEBI78653、[(2R)-2-methoxy-3-octadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate、1-O-Octadecyl-2-O-methyl-sn-glycero-3-ph

产品性质

CAS编号：77286-66-9

分子式：C27H58NO6P • XH2O

分子量：523.726（dry basis）

PubChem编号：6918215

英文别名：ET-18-OCH3|77286-66-9|(R)-edelfosine|Edelfosine, (R)-|1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholine|LZ198HY9OE|TLC-ELL-12|CHEBI78653|[(2R)-2-methoxy-3-octadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate|1-O-Octadecyl-2-O-methyl-sn-glycero-3-ph

规格或纯度：>99%

英文名称：1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine hydrate

生化机理：选择性抑制磷脂酰肌醇磷脂酶C的合成溶血磷脂类似物（成纤维细胞和腺癌细胞中IC50 =9.6μM）。也可作为血小板活化因子（PAF）受体的激动剂。抗肿瘤脂质；在肿瘤细胞中选择性诱导细胞凋亡，保留正常细胞。

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：applicationEdelfosine or 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine might be usedas a non-hydrolysable LysoPC (phospholipid) analog for analyzing its ability to block sexual commitment in Plasmodium falciparum in multilamellar vesicle preparation, to study its effect on model membranes in the selection and screening of mutagenized cells, having the ability to inhibit the transport of alkylphosphocholine drugs across the plasma membrane

PubChem SID：488195875

IUPAC Name：[(2R)-2-methoxy-3-octadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

INCHI：InChI=1S/C27H58NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-32-25-27(31-5)26-34-35(29,30)33-24-22-28(2,3)4/h27H,6-26H2,1-5H3/t27-/m1/s1

InChi Key：MHFRGQHAERHWKZ-HHHXNRCGSA-N

Canonical SMILES：CCCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC

Isomeric SMILES：CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC

PubChem CID：6918215

溶解性：溶于water, 最高浓度 (mg/mL) 2.62, 最高浓度(mM) 5 温和加热

产品包装