产品名称

英文名称：Patulin

同义词

patulin、149-29-1、Clavacin、Clavatin、Expansin、Patuline、Expansine、Claviformin、Claviform、Clairformin、Leucopin、Terinin、Gigantin、Mycoin、Mycoin C3、Penicidin、Tercinin、Mycoine C3、Mycosin、Penatin、Mycoin C、4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one、4H-Furo[3,2-c]pyran-、4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮

产品性质

CAS编号：149-29-1

分子式：C7H6O4

分子量：154.12

Beilstein号：149675

EC号：200-663-8

MDL号：MFCD00005858

PubChem编号：4696

别名：4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮

英文别名：patulin|149-29-1|Clavacin|Clavatin|Expansin|Patuline|Expansine|Claviformin|Claviform|Clairformin|Leucopin|Terinin|Gigantin|Mycoin|Mycoin C3|Penicidin|Tercinin|Mycoine C3|Mycosin|Penatin|Mycoin C|4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one|4H-Furo[3,2-c]pyran-

规格或纯度：99%

英文名称：Patulin

生化机理：真菌霉菌毒素，DNA破坏剂，诱导ROS产生。体外EGR-1依赖性ATF3上调诱导细胞凋亡。抗菌，致癌，诱变和抗癌剂。体内具有活性

应用：An inhibitor of protein prenylation

储存温度：避光,-20°C储存,干燥

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Patulin, a mycotoxin, has been reported to contain antibiotic characteristics. This compound displays the ability to specifically inhibit Na+-K+ ATPase. In murine studies, Patulin was found to inhibit protein prenylation in cells. Mechanistic studies sμggest that Patulin reduces incorporation of mevalonate into proteins and prevents protein transferase action, which is required for protein prenylation. Additional experiments show that this mycotoxin also inhibits cell-free microtubule polymerization by covalently reacting with thiol groups of microtubule proteins.An inhibitor of protein prenylationPatulin, a mycotoxin, has been reported to contain antibiotic characteristics. This compound displays the ability to specifically inhibit Na+-K+ ATPase. In murine studies, Patulin was found to inhibit protein prenylation in cells. Mechanistic studies suggest that Patulin reduces incorporation of mevalonate into proteins and prevents protein transferase action, which is required for protein prenylation. Additional experiments show that this mycotoxin also inhibits cell-free microtubule polymerization by covalently reacting with thiol groups of microtubule proteins.An inhibitor of protein prenylation

IUPAC Name：4-hydroxy-4,6-dihydrofuro[3,2-c]pyran-2-one

INCHI：InChI=1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2

InChi Key：ZRWPUFFVAOMMNM-UHFFFAOYSA-N

Canonical SMILES：C1C=C2C(=CC(=O)O2)C(O1)O

Isomeric SMILES：C1C=C2C(=CC(=O)O2)C(O1)O

WGK Germany：3

PubChem CID：4696

UN Number：3462

溶解性：Soluble in water, 100% ethanol (25 mg/mL), ethyl acetate (50 mg/mL), amyl acetate, DMSO (10 mg/mL), acetone, ethyl ether (sparingly), benzene (sparingly), and dichloromethane (10 mg/mL)

密度：1.52

敏感性：对光敏感；对湿度敏感

熔点：108-111°C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH300 Fatal if swallowed

预防措施声明：P280,P302+P352,P321,P405,P501,P264,P270,P362+P364,P330,P301+P316,P332+P317

个人防护装备：Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

产品包装