产品名称

英文名称：Alogliptin, benzoate

同义词

Alogliptin benzoate、850649-62-6、Nesina、SYR 322、SYR-322、Alogliptin (Benzoate)、(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile benzoate、Alogliptin (as benzoate)、UNII-EEN99869SC、EEN99869SC、alogliptin mon、苯甲酸阿格列汀

产品性质

CAS编号：850649-62-6

分子式：C25H27N5O4

分子量：461.522

PubChem编号：16088021

别名：苯甲酸阿格列汀

英文别名：Alogliptin benzoate|850649-62-6|Nesina|SYR 322|SYR-322|Alogliptin (Benzoate)|(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile benzoate|Alogliptin (as benzoate)|UNII-EEN99869SC|EEN99869SC|alogliptin mon

规格或纯度：99%

英文名称：Alogliptin, benzoate

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：5g、1g卖完停产，不再备货

产品介绍：Alogliptin是一种有效的，选择性的DPP-4抑制剂，IC50为<10 nM，比作用于DPP-8和DPP-9选择性高10000倍以上。Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9

IUPAC Name：2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile;benzoic acid

INCHI：InChI=1S/C18H21N5O2.C7H6O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19;8-7(9)6-4-2-1-3-5-6/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3;1-5H,(H,8,9)/t15-;/m1./s1

InChi Key：KEJICOXJTRHYAK-XFULWGLBSA-N

Canonical SMILES：CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCCC(C3)N.C1=CC=C(C=C1)C(=O)O

Isomeric SMILES：CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[C@H](C3)N.C1=CC=C(C=C1)C(=O)O

PubChem CID：16088021

溶解性：≥46.2 mg/mL in DMSO; ≥3.02 mg/mL in EtOH with gentle warming and ultrasonic; ≥46.2 mg/mL in H2O with gentle warming

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH302 Harmful if swallowed

预防措施声明：P501,P264,P260,P270,P330,P301+P317,P319

产品包装