产品名称

英文名称：Capsaicin

同义词

Capsaicin、404-86-4、(E)-Capsaicin、Zostrix、Qutenza、CAPSAICINE、Styptysat、Axsain、Isodecenoic acid vanillylamide、Ausanil、trans-Capsaicin、E-CAPSAICIN、Mioton、NGX-4010、trans-8-Methyl-N-vanillyl-6-nonenamide、FEMA No. 3404、Dolenon、Ovocap、(E)-8-Methyl-N-vanillyl-6-n、天然辣椒素

产品性质

CAS编号：404-86-4

分子式：C18H27NO3

分子量：305.41

Beilstein号：2816484

EC号：206-969-8

MDL号：MFCD00017259

PubChem编号：1548943

别名：天然辣椒素

英文别名：Capsaicin|404-86-4|(E)-Capsaicin|Zostrix|Qutenza|CAPSAICINE|Styptysat|Axsain|Isodecenoic acid vanillylamide|Ausanil|trans-Capsaicin|E-CAPSAICIN|Mioton|NGX-4010|trans-8-Methyl-N-vanillyl-6-nonenamide|FEMA No. 3404|Dolenon|Ovocap|(E)-8-Methyl-N-vanillyl-6-n

规格或纯度：分析标准品,≥95%(HPLC),

英文名称：Capsaicin

生化机理：DescriptionIC50 Value 150 ?M (MTT assay in FaDu cells) [1]Capsaicin is the active component of chili peppers, which are plantsbelonging to the genus Capsicum. Capsaicin, as a member of the vanilloidfamily, binds to a receptor called the vanilloid receptor subtype 1 (VR1). Capsaicin is able to kill prostate cancer and lung cancer cells by causing them to undergo apoptosis.in vitro Treatment of A172 cells withcapsaicin inhibited cell growth and induced apoptosis throμgh down-regulation of Bcl-2 and activation of caspase-3. Interestingly, synergistic induction of morphological alternation was observed when A172 cells were treated with capsaicin [2]. After the addition of capsaicin, the levels of reactive oxygen species were reduced slightly in the earlier stage of treatment. Interestingly, an elevation of intracellular calcium ion concentration was detected in the MCF-7 cells [3].in vivo Intraperitoneal administration of CAP (10mg/kg body weigh

应用：辣椒的活性成分，辣椒素受体激动剂，神经毒素;激活感觉神经元。

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：辣椒的活性成分，辣椒素受体激动剂，神经毒素;激活感觉神经元。

ALogP：3.6

IUPAC Name：(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide

INCHI：InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+

InChi Key：YKPUWZUDDOIDPM-SOFGYWHQSA-N

Canonical SMILES：CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC

Isomeric SMILES：CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC

WGK Germany：3

RTECS：RA8530000

PubChem CID：1548943

UN Number：2811

ChEBI：CHEBI3374

CAS Registry No.：404-86-4

ChEMBL Ligand：CHEMBL294199

BindingDB Ligand：20461

Wikipedia：Capsaicin

RCSB PDB Ligand：4DY

DrugCentral Ligand：3064

密度：1.041

闪点(℉)：235.4 °F

闪点(℃)：113℃

熔点：65°C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH301 Toxic if swallowedH302 Harmful if swallowedH318 Causes serious eye damage

预防措施声明：P280,P302+P352,P321,P405,P501,P264,P270,P362+P364,P330,P264+P265,P301+P316,P301+P317,P305+P354+P338,P317,P332+P317

Merck Index：1768

个人防护装备：Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges

产品包装