产品名称

英文名称：Mexiletine HCl

同义词

Mexiletine hydrochloride、5370-01-4、Mexiletine HCL、Mexitil、Katen、Mexiletene hydrochloride、1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride、1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride、Mexiletine (hydrochloride)、Ko 1173 Cl、2-Propanamine, 1-(2,6-di、盐酸美西律、1-(2,6-二甲基苯氧基)-2-丙胺 盐酸盐、1-(2,6-二甲基苯氧基)-2-丙胺盐酸盐 盐酸盐

产品性质

CAS编号：5370-01-4

分子式：C11H17NO·HCl

分子量：215.72

MDL号：MFCD00216024

PubChem编号：21467

别名：盐酸美西律|1-(2,6-二甲基苯氧基)-2-丙胺 盐酸盐|1-(2,6-二甲基苯氧基)-2-丙胺盐酸盐 盐酸盐

英文别名：Mexiletine hydrochloride|5370-01-4|Mexiletine HCL|Mexitil|Katen|Mexiletene hydrochloride|1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride|1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride|Mexiletine (hydrochloride)|Ko 1173 Cl|2-Propanamine, 1-(2,6-di

规格或纯度：≥98.0%(HPLC)

英文名称：Mexiletine HCl

生化机理：Mexiletine hydrochloride is a use dependent blocker of sodium channels in skeletal muscle tissue. In addition, mexiletine can plays an important role in protecting neuronal tissue from oxidative damage. The aryloxy moiety of mexiletine is very important to its function as a sodium channel blocker, as any change to this structure reduces the potency of the compound.Sodium channel blocker. Class IB anti-arrhythmic agent. Decreases action potential duration by shortening the repolarization phase.

应用：A use dependent blocker of sodium channels.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：A use dependent blocker of sodium channels.1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride (Mexiletine) is an anti-arrhythmic agent having local anaesthetic activity. Mexiletine belongs to the triclinc crystal system, with the asymmetric unit containing two independent molecules.

IUPAC Name：1-(2,6-dimethylphenoxy)propan-2-amine;hydrochloride

INCHI：InChI=1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H

InChi Key：NFEIBWMZVIVJLQ-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C(=CC=C1)C)OCC(C)N.Cl

Isomeric SMILES：CC1=C(C(=CC=C1)C)OCC(C)N.Cl

RTECS：KR9310000

PubChem CID：21467

Reaxy-Rn：4209895

溶解性：Soluble in methanol (50 mg/ml), water (100 mM), DMSO (100 mM), chloroform, and alcohol.

熔点：200-205 °C

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

Merck Index：6169

产品包装