产品名称

英文名称：Otenabant

同义词

SB22996、CP 945598、OTENABANT [WHO-DD]、1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]- 4-ethylaminopiperidine-4-carboxylic Acid Amide、FT-0746001、NCGC00351601-07、AKOS001028542、Otenabant (USAN/INN)、1-[9-(4-chloro-phenyl)-8-(2-chloro-phenyl)-9H-purin-、奥替那班

产品性质

CAS编号：686344-29-6

分子式：C25H25Cl2N7O

分子量：510.42

PubChem编号：10052040

别名：奥替那班

英文别名：SB22996|CP 945598|OTENABANT [WHO-DD]|1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]- 4-ethylaminopiperidine-4-carboxylic Acid Amide|FT-0746001|NCGC00351601-07|AKOS001028542|Otenabant (USAN/INN)|1-[9-(4-chloro-phenyl)-8-(2-chloro-phenyl)-9H-purin-

规格或纯度：≥98%

英文名称：Otenabant

生化机理：Otenabant (CP-945,598) exhibits sub-nanomolar potency at human CB1 receptors in both binding (Ki = 0.7 nM) and functional assays (Ki = 0.2 nM). The compound has low affinity (Ki = 7600 nM) for human CB2 receptors.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Otenabant (CP945598)是CB1受体高亲和性拮抗剂，Ki为0.7 nM。Otenabant (CP945598) is a recently discovered selective, high affinity, competitive CB1 receptor antagonist with Ki of 0.7 nM.

ALogP：4.3

IUPAC Name：1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide

INCHI：InChI=1S/C25H25Cl2N7O/c1-2-31-25(24(28)35)11-13-33(14-12-25)22-20-23(30-15-29-22)34(17-9-7-16(26)8-10-17)21(32-20)18-5-3-4-6-19(18)27/h3-10,15,31H,2,11-14H2,1H3,(H2,28,35)

InChi Key：UNAZAADNBYXMIV-UHFFFAOYSA-N

Canonical SMILES：CCNC1(CCN(CC1)C2=NC=NC3=C2N=C(N3C4=CC=C(C=C4)Cl)C5=CC=CC=C5Cl)C(=O)N

Isomeric SMILES：CCNC1(CCN(CC1)C2=NC=NC3=C2N=C(N3C4=CC=C(C=C4)Cl)C5=CC=CC=C5Cl)C(=O)N

PubChem CID：10052040

CAS Registry No.：686344-29-6

ChEMBL Ligand：CHEMBL562668

GPCRdb Ligand：otenabant

溶解性：DMSO

产品包装