产品名称

英文名称：Choline chloride

同义词

2-Hydroxy-N,N,N-trimethylethanaminium chloride 、 Cloruro de colina 、 2-Hydroxy-N,N,N,-trimethylethanaminium chloride 、 CHOLINE-D13 CHLORIDE 、 FT-0665025 、 Hormocline 、 CHOLINE CHLORIDE [VANDF] 、 CS-4855 、 F8889-3032 、 HMS1922E20 、 SR-01000075745 、 CHEBI1、氯化但脂,维生素B4,2-羟乙基三甲基氯化铵 、 (2-羟乙基)三甲基氯化铵

产品性质

CAS编号：67-48-1

分子式：C5H14ClNO

分子量：139.62

Beilstein号：3563126

EC号：200-655-4

MDL号：MFCD00011721

PubChem编号：6209

别名：氯化但脂,维生素B4,2-羟乙基三甲基氯化铵 | (2-羟乙基)三甲基氯化铵

英文别名：2-Hydroxy-N,N,N-trimethylethanaminium chloride | Cloruro de colina | 2-Hydroxy-N,N,N,-trimethylethanaminium chloride | CHOLINE-D13 CHLORIDE | FT-0665025 | Hormocline | CHOLINE CHLORIDE [VANDF] | CS-4855 | F8889-3032 | HMS1922E20 | SR-01000075745 | CHEBI1

规格或纯度：用于细胞和昆虫细胞培养,≥99%

英文名称：Choline chloride

生化机理：The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .

应用：Choline acetyltransferase substrate A source of methyl groups for methyl-transfer reactions. Biochem/physiol Actions Acyl group acceptor

储存温度：充氩,干燥

运输条件：常规运输

产品介绍：微有鱼腥臭，具咸苦味。易潮解。易溶于水及醇，水溶液几乎呈中性，不溶于醚、石油醚、苯及二硫化碳。在碱性中不稳定。胆碱是鞘磷脂和卵磷脂的成分。它是乙酰胆碱的前体。胆碱在甲基代谢、致癌作用和脂质转运中具有至关重要的作用。胆碱缺乏与脂肪肝有关。它能维持细胞结构完整性和细胞信号传导。胆碱参与磷脂的合成。它是缺血性心脏病的有效生物标志物。应用氯化胆碱已被用于胆碱释放测定作为σ-1受体（Sig-1Rs）的内源性激动剂作为分析蛋氨酸与胆碱代谢之间相互关系的标准品Choline is a constituent of sphingomyelin and lecithin. It is a precursor of acetylcholine. Choline plays a vital role in methyl group metabolism, carcinogenesis and lipid transport. Choline deficiency is associated with fatty liver. It maintains cell structural integrity and cell signalling. Choline is implicated in the synthesis of phospholipids. It acts as a potent biomarker for ischemic heart disease.ApplicationCholine chloride has been usedin choline release assayas an endogenous agonist of sigma-1 receptors (Sig-1Rs)as a standard to analyse interrelationships between methionine and choline metabolism

IUPAC Name：2-hydroxyethyl(trimethyl)azanium;chloride

INCHI：InChI=1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChi Key：SGMZJAMFUVOLNK-UHFFFAOYSA-M

Canonical SMILES：C[N+](C)(C)CCO.[Cl-]

Isomeric SMILES：C[N+](C)(C)CCO.[Cl-]

WGK Germany：1

RTECS：KH2975000

PubChem CID：6209

Reaxy-Rn：3563126

溶解性：可溶于水、乙醇和甲醇。

密度：1.205

敏感性：易吸潮

熔点：302-305°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

Merck Index：2206

个人防护装备：dust mask type N95 (US),Eyeshields,Gloves

产品包装