产品名称

英文名称：Ziprasidone HCl

同义词

Ziprasidone hydrochloride、122883-93-6、Ziprasidone HCl、Geodon、Zeldox、5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one hydrochloride、Ziprasidone (hydrochloride)、5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-d、5-[2-[4-(1,2-苯并异噻唑-3-基)-1-哌嗪基]乙基]-6-氯-1,3-二氢-2H-吲哚-2-酮盐酸盐、盐酸齐拉西酮

产品性质

CAS编号：122883-93-6

分子式：C21H21ClN4OS·HCl

分子量：449.4

PubChem编号：219099

别名：5-[2-[4-(1,2-苯并异噻唑-3-基)-1-哌嗪基]乙基]-6-氯-1,3-二氢-2H-吲哚-2-酮盐酸盐|盐酸齐拉西酮

英文别名：Ziprasidone hydrochloride|122883-93-6|Ziprasidone HCl|Geodon|Zeldox|5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one hydrochloride|Ziprasidone (hydrochloride)|5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-d

规格或纯度：≥98%

英文名称：Ziprasidone HCl

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Ziprasidone hydrochloride是 5-HT (serotonin) 和多巴胺受体(dopamine receptor) 拮抗剂。Ziprasidone hydrochloride 对大鼠 (Ki 3.4 nM) 和人 (2.5 nM) 5-HT1A，5-HT2A (0.42 nM) 和 dopamine D2 (4.8 nM) 受体有很高的亲和力。Ziprasidone hydrochloride 是一种去甲肾上腺素再摄取 (norepinephrine reuptake) 抑制剂。Ziprasidone hydrochloride is a combined 5-HT (serotonin) and dopamine receptor antagonist. Ziprasidone hydrochloride has high affinity for rat (Ki 3.4 nM)/human (2.5 nM) 5-HT1A receptors, 5-HT2A (0.42 nM), and dopamine D2 receptors (4.8 nM). Ziprasidone hydrochloride is an inhibitor of norepinephrine reuptake.

IUPAC Name：5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one;hydrochloride

INCHI：InChI=1S/C21H21ClN4OS.ClH/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21;/h1-4,11,13H,5-10,12H2,(H,23,27);1H

InChi Key：NZDBKBRIBJLNNT-UHFFFAOYSA-N

Canonical SMILES：C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.Cl

Isomeric SMILES：C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.Cl

PubChem CID：219099

溶解性：DMSO 90 mg/mL (200.26 mM);Water <1 mg/mL (<1 mM);Ethanol <1 mg/mL (<1 mM)

产品包装