产品名称

英文名称：Piribedil

同义词

piribedil、3605-01-4、Trivastal、Trivastan、2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine、ET-495、EU-4200、2-(4-Piperonyl-1-piperazinyl)pyrimidine、2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine、ET 495、EU 4200、DO22K1PRDJ、1-(2-Pyrimid、2-[4-(1,3-苯并二唑-5-基甲基)-1-哌嗪基]嘧啶、双哌嘧啶、泰舒达

产品性质

CAS编号：3605-01-4

分子式：C16H18N4O2

分子量：298.35

MDL号：MFCD00868264

PubChem编号：4850

别名：2-[4-(1,3-苯并二唑-5-基甲基)-1-哌嗪基]嘧啶|双哌嘧啶|泰舒达

英文别名：piribedil|3605-01-4|Trivastal|Trivastan|2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine|ET-495|EU-4200|2-(4-Piperonyl-1-piperazinyl)pyrimidine|2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine|ET 495|EU 4200|DO22K1PRDJ|1-(2-Pyrimid

规格或纯度：>98.0%(HPLC)

英文名称：Piribedil

生化机理：Piribedil is a potent and orally active dopamine D2 and dopamine D3 agonist. Piribedil is also a α2-adrenoceptors antagonist. Piribedil can inhibit MLL1 methyltransferase activity (EC50 0.18 μM). Piribedil has the potential for the research of parkinson's disease, circulatory disorders, cancers.

运输条件：常规运输

产品介绍：产品介绍Piribedil 是一种有效且具有口服活性的多巴胺 D2 (dopamine D2) 和 多巴胺 D3 (dopamine D3) 激动剂。Piribedil 也是一种 α2-肾上腺素受体 (α2-adrenoceptors) 拮抗剂。Piribedil 可抑制 MLL1 甲基转移酶的活性 (EC50 0.18 μM)。Piribedil 可用于研究帕金森病，循环系统疾病，癌症。

PubChem SID：488179860

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488179860

IUPAC Name：2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine

INCHI：InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2

InChi Key：OQDPVLVUJFGPGQ-UHFFFAOYSA-N

Canonical SMILES：C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC=CC=N4

Isomeric SMILES：C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC=CC=N4

PubChem CID：4850

Wikipedia：Piribedil

CAS Registry No.：3605-01-4

ChEMBL Ligand：CHEMBL1371770

DrugCentral Ligand：2202

GPCRdb Ligand：piribedil

溶解性：DMSO54 mg/mL(181 mM)；ChloroformSoluble

熔点：98 °C

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH412 Harmful to aquatic life with long lasting effectsH302 Harmful if swallowedH336 May cause drowsiness or dizzinessH362 May cause harm to breast-fed children

预防措施声明：P261,P273,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P330,P263,P203,P301+P317,P318,P319

Merck Index：7493

产品包装