产品名称

英文名称：Vortioxetine

同义词

Lu AA 21004、AR-270/43507985、GG-0052、Lu AA 21004、Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-; 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine; Lu AA 21004; Vortioxetine、VORTIOXETINE [INN]、FS-3517、1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazin、沃替西汀

产品性质

CAS编号：508233-74-7

分子式：C18H22N2S

分子量：298.45

EC号：823-919-6

PubChem编号：9966051

别名：沃替西汀

英文别名：Lu AA 21004|AR-270/43507985|GG-0052|Lu AA 21004|Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-; 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine; Lu AA 21004; Vortioxetine|VORTIOXETINE [INN]|FS-3517|1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazin

规格或纯度：≥98%

英文名称：Vortioxetine

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) Target 5-HT receptor

PubChem SID：488196483

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488196483

IUPAC Name：1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine

INCHI：InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3

InChi Key：YQNWZWMKLDQSAC-UHFFFAOYSA-N

Canonical SMILES：CC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C

Isomeric SMILES：CC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C

关联CAS：508233-74-7

PubChem CID：9966051

MeSH Entry Terms：1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine;brintellix;Lu AA21004;Lu-AA21004;LuAA21004;vortioxetine;vortioxetine hydrobromide

Wikipedia：Vortioxetine

CAS Registry No.：508233-74-7

ChEMBL Ligand：CHEMBL2104993

PEP：vortioxetine

DrugCentral Ligand：4806

GPCRdb Ligand：vortioxetine

溶解性：≥ 14.9 mg/mL in DMSO；≥ 4.31 mg/mL in EtOH with ultrasonic；insoluble in H2O

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH361 Suspected of damaging fertility or the unborn childH371 May cause damage to organs

预防措施声明：P280,P405,P501,P264,P260,P270,P203,P318,P308+P316,P319

产品包装