产品名称

英文名称：N-Succinimidyl S-Acetylthioglycolate

同义词

76931-93-6、SATA、N-Succinimidyl-S-acetylthioacetate、2,5-Dioxopyrrolidin-1-yl 2-(acetylthio)acetate、N-Succinimidyl S-acetylthioglycolate、(2,5-dioxopyrrolidin-1-yl) 2-acetylsulfanylacetate、SATA Protein Modifier、N-Succinimidyl S-acetylthioacetate、N-Hydroxysuc、S-乙酰硫基乙酸琥珀酰亚胺酯、SATA

产品性质

CAS编号：76931-93-6

分子式：C8H9NO5S

分子量：231.22

Beilstein号：7815490

MDL号：MFCD00036891

PubChem编号：127532

别名：S-乙酰硫基乙酸琥珀酰亚胺酯|SATA

英文别名：76931-93-6|SATA|N-Succinimidyl-S-acetylthioacetate|2,5-Dioxopyrrolidin-1-yl 2-(acetylthio)acetate|N-Succinimidyl S-acetylthioglycolate|(2,5-dioxopyrrolidin-1-yl) 2-acetylsulfanylacetate|SATA Protein Modifier|N-Succinimidyl S-acetylthioacetate|N-Hydroxysuc

规格或纯度：>94.0%(GC)

英文名称：N-Succinimidyl S-Acetylthioglycolate

生化机理：伯胺反应性蛋白修饰硫醇化试剂。将受保护的巯基添加到目标蛋白质中。通过在相邻TNF-α分子上的反应性巯基之间形成二硫键，诱导稳定的重组TNF-α三聚体形成

应用：Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjμgates and hapten carrier molecule conjμgates.Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

IUPAC Name：(2,5-dioxopyrrolidin-1-yl) 2-acetylsulfanylacetate

INCHI：InChI=1S/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3

InChi Key：FLCQLSRLQIPNLM-UHFFFAOYSA-N

Canonical SMILES：CC(=O)SCC(=O)ON1C(=O)CCC1=O

Isomeric SMILES：CC(=O)SCC(=O)ON1C(=O)CCC1=O

WGK Germany：3

PubChem CID：127532

Reaxy-Rn：7815491

溶解性：solubility acetonitrile 50 mg/mL;DMF soluble;

敏感性：对热敏感;对湿度敏感

熔点：95 - 101°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：Eyeshields， Gloves， type N95 (US)， type P1 (EN143) respirator filter

产品包装