产品名称

英文名称：BMS-754807

同义词

BMS-754807、1001350-96-4、BMS 754807、BMS754807、UNII-W9E3353E8J、CHEMBL575448、W9E3353E8J、(S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide、namide、CHEBI88339、(2S)-1-[4-

产品性质

CAS编号：1001350-96-4

分子式：C23H24FN9O

分子量：461.49

PubChem编号：24785538

英文别名：BMS-754807|1001350-96-4|BMS 754807|BMS754807|UNII-W9E3353E8J|CHEMBL575448|W9E3353E8J|(S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide|namide|CHEBI88339|(2S)-1-[4-

规格或纯度：98%

英文名称：BMS-754807

生化机理：BMS-754807 is an orally bioavailable antagonist of human insulin-like growth factor type I receptor (IGF-1R) with potential antineoplastic activity.

储存温度：-20°C储存

运输条件：超低温冰袋运输

IUPAC Name：(2S)-1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide

INCHI：InChI=1S/C23H24FN9O/c1-23(21(34)26-15-7-8-18(24)25-13-15)9-3-10-32(23)22-28-20(17-4-2-11-33(17)31-22)27-19-12-16(29-30-19)14-5-6-14/h2,4,7-8,11-14H,3,5-6,9-10H2,1H3,(H,26,34)(H2,27,28,29,30,31)/t23-/m0/s1

InChi Key：LQVXSNNAFNGRAH-QHCPKHFHSA-N

Canonical SMILES：CC1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F

Isomeric SMILES：C[C@]1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F

PubChem CID：24785538

ChEMBL Ligand：CHEMBL575448

CAS Registry No.：1001350-96-4

RCSB PDB Ligand：EBI

溶解性：DMSO 92 mg/mL Water <1 mg/mL Ethanol 92 mg/mL

产品包装