产品名称

英文名称：cenicriviroc

同义词

Cenicriviroc、497223-25-3、TBR-652、TAK-652、TBR652、TBR 652、15C116UA4Y、497223-25-3 (free base)、(-)-8-(4-(2-butoxyethoxy)phenyl)-1-isobutyl-n-(4-(((1-propyl-1H-imidazol-5-yl)methyl)sulfinyl)phenyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide、(S,E)-8-(4-(2-b

产品性质

CAS编号：497223-25-3

分子式：C41H52N4O4S

分子量：696.95

PubChem编号：11285792

英文别名：Cenicriviroc|497223-25-3|TBR-652|TAK-652|TBR652|TBR 652|15C116UA4Y|497223-25-3 (free base)|(-)-8-(4-(2-butoxyethoxy)phenyl)-1-isobutyl-n-(4-(((1-propyl-1H-imidazol-5-yl)methyl)sulfinyl)phenyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide|(S,E)-8-(4-(2-b

规格或纯度：97%

英文名称：cenicriviroc

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：applicationCenicriviroc is an experimental drug candidate for the treatment of HIV infection. It is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell.general descriptionCenicriviroc (CVC, TAK-652, TBR-652) is a potent inhibitor of CC chemokine receptor 2 (CCR2) and CCR5. Cenicriviroc also inhibits HIV-1 and HIV-2 with potent anti-inflammatory and antiinfective activity.

ALogP：7.5

IUPAC Name：(5E)-8-[4-(2-butoxyethoxy)phenyl]-1-(2-methylpropyl)-N-[4-[(S)-(3-propylimidazol-4-yl)methylsulfinyl]phenyl]-3,4-dihydro-2H-1-benzazocine-5-carboxamide

INCHI：InChI=1S/C41H52N4O4S/c1-5-7-22-48-23-24-49-38-15-10-32(11-16-38)33-12-19-40-35(25-33)26-34(9-8-21-44(40)28-31(3)4)41(46)43-36-13-17-39(18-14-36)50(47)29-37-27-42-30-45(37)20-6-2/h10-19,25-27,30-31H,5-9,20-24,28-29H2,1-4H3,(H,43,46)/b34-26+/t50-/m0/s1

InChi Key：PNDKCRDVVKJPKG-WHERJAGFSA-N

Canonical SMILES：CCCCOCCOC1=CC=C(C=C1)C2=CC3=C(C=C2)N(CCCC(=C3)C(=O)NC4=CC=C(C=C4)S(=O)CC5=CN=CN5CCC)CC(C)C

Isomeric SMILES：CCCCOCCOC1=CC=C(C=C1)C2=CC/3=C(C=C2)N(CCC/C(=C3)/C(=O)NC4=CC=C(C=C4)[S@@](=O)CC5=CN=CN5CCC)CC(C)C

PubChem CID：11285792

ChEMBL Ligand：CHEMBL2110727

BindingDB Ligand：50184403

Wikipedia：Cenicriviroc

CAS Registry No.：497223-25-3

GPCRdb Ligand：cenicriviroc

溶解性：Insoluble in water;100 mg/mL(143.48 mM) in DMSO and ethanol;

产品包装