产品名称

英文名称：Ki16198

同义词

Propanoic acid, 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]-, methyl ester、Propanoic acid, 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]-, methyl ester

产品性质

CAS编号：355025-13-7

分子式：C24H25ClN2O5S

分子量：488.98

PubChem编号：9913405

别名：Propanoic acid, 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]-, methyl ester

英文别名：Propanoic acid, 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]-, methyl ester

规格或纯度：98%

英文名称：Ki16198

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：说明Ki16198是Ki16425的甲酯，是LPA拮抗剂，抑制LPA1-和LPA3诱导的肌醇磷酸产生，Ki分别为0.34 μM和0.93 μM，对LPA2具有较弱的抑制作用，对LPA4， LPA5， LPA6没有抑制活性。Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6.

IUPAC Name：methyl 3-[[4-[4-[1-(2-chlorophenyl)ethoxycarbonylamino]-3-methyl-1,2-oxazol-5-yl]phenyl]methylsulfanyl]propanoate

INCHI：InChI=1S/C24H25ClN2O5S/c1-15-22(26-24(29)31-16(2)19-6-4-5-7-20(19)25)23(32-27-15)18-10-8-17(9-11-18)14-33-13-12-21(28)30-3/h4-11,16H,12-14H2,1-3H3,(H,26,29)

InChi Key：HHVJBROTJWPHHX-UHFFFAOYSA-N

Canonical SMILES：CC1=NOC(=C1NC(=O)OC(C)C2=CC=CC=C2Cl)C3=CC=C(C=C3)CSCCC(=O)OC

Isomeric SMILES：CC1=NOC(=C1NC(=O)OC(C)C2=CC=CC=C2Cl)C3=CC=C(C=C3)CSCCC(=O)OC

PubChem CID：9913405

溶解性：DMSO 96 mg/mL Water <1 mg/mL Ethanol 35 mg/mL

产品包装