嘧啶-4-硼酸

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产品名称

中文名称：嘧啶-4-硼酸

英文名称：Pyrimidin-4-ylboronic Acid (~80%)

产品性质

产品编号：LY-TRCP997335

CAS 号：852362-24-4

英文名称：Pyrimidin-4-ylboronic Acid (~80%)

中文名称：嘧啶-4-硼酸

分子式：C4H5BN2O2

分子量：123.91

存储条件：4℃

性状：White to Off-White Solid

溶解性：DMSO (Slightly), Methanol (Slightly)

类别：Building Blocks; Miscellaneous;

应用：Pyrimidin-4-ylboronic Acid is an intermediate used to prepare aldosterone synthase inhibiting pyrimidinylnaphthalenes via Suzuki cross-coupling reactions. It is also used in the synthesis of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine as a potent, orally active Src kinase inhibitor with antitumor activity.

参考文献：Voets, M., et al.; J. Med. Chem., 48, 6632 (2005); Noronha, G., et al. Bioorg. Med. Chem. Lett., 17, 602 (2007) 展开

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