18:0-18:1 PA

别名

1-octadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); SOPA; PA(18:0/18:1(9Z))

一般描述

18:0-18:1 PA (1-stearoyl-2-oleoyl-sn-glycero-3-phosphate) is an unsaturated phosphatidic acid (PA) derivative. PA is present in the biomembranes. It is the simplest glycerophospholipid.

应用

18:0-18:1 PA (1-stearoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)) may be used:
as a phosphatidic acid (PA) standard to identify the corresponding radiolabeled PA on the thin-layer chromatography (TLC) in vesicles for experimental validation in order to identify novel phospholipids capable of inhibiting cellular membrane transportation by (ATP)-binding cassette P-glycoprotein (P-gp)to treat young adult mouse colonic (YAMC) cells prior to nanoclustering- forster resonance energy transfer (FRET) analysis(6)

生化/生理作用

Phosphatidic acid (PA) is the precursor for other phospholipids and acts as a signaling molecule.