L-741,626

别名

(±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole

溶解性

DMSO: ≥20 mg/mL
ethanol: 24 mg/mL
H2O: insoluble

应用

L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.

生化/生理作用

L-741,626 is a selective dopamine (D2) receptor antagonist.

特点和优势

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.