Azelaoyl-PAF

一般描述

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF is a low molecular weight phospholipid.

应用

Azelaoyl-PAF may be used in binding assay of anti-inflammatory peptides, 2F and 4F.

生化/生理作用

1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) acts as an agonist for peroxisome proliferator-activated receptors γ(PPAR-γ). It may be used as a therapeutic for Friedreich′s ataxia (FRDA). At low concentrations azelaoyl-PAF may induce apoptosis.