Brilliant Black BN

应用

Brilliant Black BN has been used:
in micronucleus and comet assays to evaluate its genotoxic effect.as a quenching agent in calcium mobilization assay.as a redox indicator in microbiological inhibition bioassay using Bacillus megaterium to detect tetracycline and macrolides in milk.

生化/生理作用

[4-acetamido-5-hydroxy-6-[7-sulfonato-4-(4-sulfonatophenylazo)-1-naphtylazo], also known as food black 1, belongs to the group of azo dyes. Brilliant Black BN is widely used as a food dye and pharmaceutical excipient. In addition, it also acts as an allosteric modulator of the adenosine A1 and A3 receptors and is generally used within calcium mobilization assays to reduce extracellular fluorescence.