盐酸芬戈莫德

中文名称：盐酸芬戈莫德

英文名称： Fingolimod hydrochloride

CAS： 162359-56-0

分子式： C₁₉H₃₄ClNO₂

分子量： 344

EINECS号： 680-631-1

中文同义词盐酸芬戈莫德英文同义词

Fingolimod hydrochloride

基本性质

溶解度	water: soluble10mg/mL, clear
形态	powder
颜色	white to beige

安全信息

危险品标志	Xi
危险类别码	36/37/38-52/53
安全说明	26-61
RTECS号	TY3130000
海关编码	29221990
毒性	LD50 orally in rats: 300-600 mg/kg (Troncoso)

CHS信息

危险性符号(GHS)	GHS08

生产方法及用途

用途	一种S1P拮抗剂，在K562和NK细胞中IC50为0.33nM。 FTY720 is an aminopropanediol cell-permeable EDG-1 (endothelial differential gene 1 receptor) antagonist and immunosuppresive agent. It has been shown to display lymphocyte, or white blood cell, sequestration properties. When FTY720 is phosphorylated, it becomes an agonist for four sphingosine 1-phosphate receptors. FTY720 is an inhibitor of cPLA2.

用途

一种S1P拮抗剂，在K562和NK细胞中IC50为0.33nM。
FTY720 is an aminopropanediol cell-permeable EDG-1 (endothelial differential gene 1 receptor) antagonist and immunosuppresive agent. It has been shown to display lymphocyte, or white blood cell, sequestration properties. When FTY720 is phosphorylated, it becomes an agonist for four sphingosine 1-phosphate receptors. FTY720 is an inhibitor of cPLA2.