L-环丝氨酸

中文名称： L-环丝氨酸

英文名称： L-Cycloserine

CAS： 339-72-0

分子式： C₃H₆N₂O₂

分子量： 102

EINECS号： 206-427-0

中文同义词 L-环丝氨酸英文同义词

L-Cycloserine

基本性质

折射率	1.5110 (estimate)
溶解度	H2O: soluble50mg/mg protein
形态	White to off-white powder.
酸度系数(pKa)	14.36±0.40(Predicted)
颜色	White to Off-White
BRN	80799
PubChem编号	449215
规格或纯度	97%
运输条件	冰袋运输
IUPAC Name	(4S)-4-amino-1,2-oxazolidin-3-one
折光率	1.48

安全信息

危险品标志	Xn
安全说明	38-36/37
WGK Germany	2
RTECS号	NY2976000
F	10

CHS信息

生产方法及用途

产品介绍	L-Cycloserine ((S)-4-Amino-3-isoxazolidone) 作用于大肠杆菌和各种动物大脑, 不可逆地抑制 GABA 5'-磷酸吡哆醛氨基转移酶, 这种作用具有时间依赖性, 导致了γ-氨基丁酸 (GABA) 含量增高, GABA 在体内抑制性神经递质L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase, which is the first enzyme of the sphingolipid pathway, and causes the synthesis of sphingolipids to decrease. In vitro studies demonstrated that L-cyloserine inhibits 3-ketodihydrosphingosine synthetase 100 times more than D-Cycloserine .Research regarding L-Cycloserine and its effect on the immune response suggest that L-Cycloserine increases the level of IL-4 producing helper T cells and suppress the adhesion molecules CD29 and CD98. L-Cycloserine also inhibits SPTLC (serine palmitoyltransferase (SPT)), and HIV-1 investigations in the CD4+ lymphoid cell line (CEM) have shown that L-Cycloserine can inhibit HIV-1 replication.An irreversible inhibitor of 3-ketodihydrosphingosine synthetase

产品介绍

L-Cycloserine ((S)-4-Amino-3-isoxazolidone) 作用于大肠杆菌和各种动物大脑, 不可逆地抑制 GABA 5'-磷酸吡哆醛氨基转移酶, 这种作用具有时间依赖性, 导致了γ-氨基丁酸 (GABA) 含量增高, GABA 在体内抑制性神经递质L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase, which is the first enzyme of the sphingolipid pathway, and causes the synthesis of sphingolipids to decrease. In vitro studies demonstrated that L-cyloserine inhibits 3-ketodihydrosphingosine synthetase 100 times more than D-Cycloserine .Research regarding L-Cycloserine and its effect on the immune response suggest that L-Cycloserine increases the level of IL-4 producing helper T cells and suppress the adhesion molecules CD29 and CD98. L-Cycloserine also inhibits SPTLC (serine palmitoyltransferase (SPT)), and HIV-1 investigations in the CD4+ lymphoid cell line (CEM) have shown that L-Cycloserine can inhibit HIV-1 replication.An irreversible inhibitor of 3-ketodihydrosphingosine synthetase