Stattic

中文名称： Stattic

英文名称： Stattic

CAS： 19983-44-9

分子式： C₈H₅NO₄S

分子量： 211

EINECS号：

中文同义词英文同义词

Stattic

基本性质

溶解度	DMSO: >20mg/mL
形态	powder
颜色	white to beige

安全信息

危险品标志	Xi,Xn
安全说明	26-36/37/39
Hazard Note	Irritant
海关编码	2934999090

CHS信息

危险性符号(GHS)	GHS07

生产方法及用途

用途	一种有效的STAT3活化和二聚化的抑制剂。Stattic is a small molecule shown to selectively inhibit the activation of the Stat3 transcription factor by blocking phosphorylation and dimerization events. Stattic has been used as a tool for probing the upstream activation of this factor, significantly expressed in many cancer cell lines, and interruption of this pathway in breast cancer cell lines lead to an increased apoptotic rate in these cells. Stat3 Inhibitor V, Stattic is an inhibitor of Stat3.

用途

一种有效的STAT3活化和二聚化的抑制剂。Stattic is a small molecule shown to selectively inhibit the activation of the Stat3 transcription factor by blocking phosphorylation and dimerization events. Stattic has been used as a tool for probing the upstream activation of this factor, significantly expressed in many cancer cell lines, and interruption of this pathway in breast cancer cell lines lead to an increased apoptotic rate in these cells. Stat3 Inhibitor V, Stattic is an inhibitor of Stat3.