阿洛司他丁

中文名称：阿洛司他丁

英文名称： EST

CAS： 88321-09-9

分子式： C₁₇H₃₀N₂O₅

分子量： 342

EINECS号：

中文同义词阿洛司他丁英文同义词

EST

基本性质

折射率	1.5800 (estimate)
溶解度	Soluble in DMSO, DMF or ethanol
形态	White solid
酸度系数(pKa)	13.32±0.40(Predicted)
颜色	Fine needles from EtOH

安全信息

危险品标志	Xi
安全说明	26-36-24/25
危险品运输编号	3077
海关编码	29242990
毒性	cyt-ham:lng 200 mg/L IYKEDH 17,815,86

CHS信息

生产方法及用途

用途	一种cysteine protease(半胱氨酸蛋白酶)抑制剂。 The compound can permeate an intact cell and block the activity of calpain, which results in the protection of protein kinase C (PKC) from proteolysis. E-64-d is also a cathepsin B, cathepsin H, and cathepsin L inhibitor. Research shows that E-64-d can enhance compromised natural killer cells and bactericidal activity of leukocytes. In addition, E-64-d has been shown to induce cell cycle arrest during prophase and metaphase in Xenopus embryonic cells.

用途

一种cysteine protease(半胱氨酸蛋白酶)抑制剂。
The compound can permeate an intact cell and block the activity of calpain, which results in the protection of protein kinase C (PKC) from proteolysis. E-64-d is also a cathepsin B, cathepsin H, and cathepsin L inhibitor. Research shows that E-64-d can enhance compromised natural killer cells and bactericidal activity of leukocytes. In addition, E-64-d has been shown to induce cell cycle arrest during prophase and metaphase in Xenopus embryonic cells.