3-[(3-氯-4-羟苯基)氨基]-4-(2-硝苯基)-1H-吡咯-2,5-二酮

中文名称： 3-[(3-氯-4-羟苯基)氨基]-4-(2-硝苯基)-1H-吡咯-2,5-二酮

英文名称： SB 415286

CAS： 264218-23-7

分子式： C₁₆H₁₀ClN₃O₅

分子量： 360

EINECS号：

中文同义词 3-[(3-氯-4-羟苯基)氨基]-4-(2-硝苯基)-1H-吡咯-2,5-二酮英文同义词

SB 415286

基本性质

溶解度	DMSO: 16 mg/mL
形态	Yellow Solid.
酸度系数(pKa)	6.81±0.60(Predicted)
颜色	yellow to orange
PubChem编号	4210951
规格或纯度	98%
运输条件	超低温冰袋运输
IUPAC Name	3-(3-chloro-4-hydroxyanilino)-4-(2-nitrophenyl)pyrrole-2,5-dione

安全信息

危险品标志	Xi
安全说明	26-36
WGK Germany	3

CHS信息

危险性符号(GHS)	GHS07
警示词	Warning

生产方法及用途

存储条件	-20°C储存
产品介绍	产品介绍SB 415286 is apotent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and aKi of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β.产品用途SB 415286 was used to treat neuroblastoma cells and study the effect of GSK-3 inhibition on cell proliferation.Product IntroductionSB 415286 is apotent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and aKi of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β.Product UsageSB 415286 was used to treat neuroblastoma cells and study the effect of GSK-3 inhibition on cell proliferation.

存储条件

-20°C储存

产品介绍

产品介绍SB 415286 is apotent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and aKi of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β.产品用途SB 415286 was used to treat neuroblastoma cells and study the effect of GSK-3 inhibition on cell proliferation.Product IntroductionSB 415286 is apotent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and aKi of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β.Product UsageSB 415286 was used to treat neuroblastoma cells and study the effect of GSK-3 inhibition on cell proliferation.